By Thapar M.R.
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Additional info for AVO and Seismic Attributes: Principles and Applications - Course Notes
Toomre, D. (2000). Lipid rafts and signal transduction. Nature Rev. 1, 31–39. L. (1972). The fluid mosaic model of the structure of cell membranes. Science 175, 720–731. C. (2002). Peroxisomal localization of inducible nitric oxide synthase in hepatocytes. Hepatology 36, 81–93. Baltimore, MD. A. (2006). Peroxisomes and aging. Biochim. Biophys. Acta 1763, 1749–1754. M. (2004). Mechanotransduction through growth-factor shedding into the extracellular space. Nature 429, 83–86. , Damjanovich, S. (2003).
Rev. Physiol. Biochem. Pharmacol. 132, 1–77. C. (1996). Activation of MEK-1 and SEK-1 by Tpl-2 proto-oncoprotein, a novel MAP kinase kinase kinase. EMBO J. 15, 817–826. P. (2004). Mechanical stretch induces fetal type II cell differentiation via an epidermal growth factor receptor-extracellular-regulated protein kinase signaling pathway. Am. J. Resp. Cell Mol. Biol. 30, 76–83. D. (2006). Peroxisomes and oxidative stress. Biochim. Biophys. Acta 1763, 1755–1766. , Toomre, D. (2000). Lipid rafts and signal transduction.
Peroxisomes not only participate in the generation of ROS, but also have scavenging activities to metabolize these reactive oxygen molecules. When PPARs become activated, the expression of genes involved in lipid β-oxidation is strongly enhanced (up to 10-fold), while the induction of hydrogen peroxide scavenging genes such as catalase is not (1- to 2-fold) (Rao and Reddy, 1987). Since a number of xenobiotics induce PPARs including hypolipidemic drugs, industrial chemicals, agrochemicals, and many environmental pollutants (Beier and Fahimi, 1991), it has been proposed that the tumor-promoting properties of these compounds is caused by the disproportionate production of hydrogen peroxidegenerating enzymes over scavenging enzymes, leading to oxidative stress and eventually leading to hepatic tumors in animals (Schrader and Fahimi, 2006).
AVO and Seismic Attributes: Principles and Applications - Course Notes by Thapar M.R.
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