By Stephen J. Lippard (auth.), Dimitris P. Kessissoglou (eds.)

ISBN-10: 940104113X

ISBN-13: 9789401041133

ISBN-10: 9401102554

ISBN-13: 9789401102551

Bioinorganic chemistry is basically interested by the position of steel atoms in biology and is a really lively study box. notwithstanding, even if such vital constructions of metalloenzymes are recognized, because the MoFeCo of nitrogenase, Cu or Mn superoxide dismutase and plastocyanin, the bogus routes to the modelling of such facilities continues to be an issue of acute clinical curiosity. different metalloenzymes, resembling the Mn heart of the oxygen evolving complicated of PSII, are nonetheless the point of interest of in-depth exam, either spectroscopic and structural. one other zone of shock is the interplay among medicines and metals and steel ion antagonism. knowing the chemistry of steel ions in organic platforms will deliver advantages by way of knowing such difficulties as biomineralization and the creation of complex fabrics via micro-organisms.
The 29 contributions to Bioinorganic Chemistry: An Inorganic standpoint of Life supply a very good precis of the cutting-edge during this box, masking components from the NMR of paramagnetic molecules to using lanthanide porphyrins in man made batteries.

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Extra resources for Bioinorganic Chemistry: An Inorganic Perspective of Life

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3~ This is due to the enterobactin molecule binding to sero albumin, effectively removing it from solution. Enterobactin is a hapten as weIl, and stimulates antibody production. 33. Aerobactin is in some ways a more efficient siderophore. Production of the sideroy'hore and excretion into solution is more rapid than enterobactin in response to iron stress-'~ and aerob actin is recycled. 35. Once aerob actin delivers iron to the ceIl, the aerobactin molecule is re-excreted. Experimental evidence corroborates that it is the production of aerobactin, and not enterobactin, that enhances vimlence.

1988, 27,1436. (26) Baker, E. ; Anderson, B. ; Baker, H. ; Norris, G. ; Rumball, S. ; Smith, C. A, Pure & Appl. Chem. 1990,62, 1067. ; Evans, R. ; Garrett, R. ; Lindley, P. ; Watson, J. , Biochemistry, 1988, 27,5804. (28) Anderson, B. ; Baker, H. ; Norris, G. ; Rumball, S. ; Baker, E. , Nature 1990, 344, 784. ; Leibman, A, Biochim. Biophys. Acta 1972,257,314. (30) Chung, T. D. ; Raymond, K. , 1. Am. Chem. Soc. 1993, J15, 6765 .. SIDEROPHORE-MEDIATED IRON TRANSPORT IN MICROBES KENNETH N. RAYMOND and JASON R.

Liu, K. ; Johnson, C. ; Lippard, S. J. J. Arn. Chern. Soc. 1993,115,939. ; Fox, B. ; Froland, W. ; Lipscomb, J. ; Münck, E. J. Am. ehem. Soc. 1993,115,6450. ; Nesheim, J. ; Lipscomb, J. D. J. Biol. ehem. 1993,268, 21569. Liu, K. ; Huynh, B. ; Edmondson, D. ; Lippard, S. J. 1994, submitted for publication. Kunz, D. M. ehem. Rev. 1990, 90, 585. Liu, K. ; Lippard, S. , unpublished results. Priestley, N. ; Floss, H. ; Froland, W. ; Lipscomb, J. ; Williams, P. ; Morimoto, H. J. Am. ehem. Soc. 1992,114, 7561.

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Bioinorganic Chemistry: An Inorganic Perspective of Life by Stephen J. Lippard (auth.), Dimitris P. Kessissoglou (eds.)


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