By National Council on Radiation Protection and Measurements

ISBN-10: 0913392804

ISBN-13: 9780913392805

ISBN-10: 1435629523

ISBN-13: 9781435629523

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Extra info for Biological Effects and Exposure Criteria for Radiofrequency Electromagnetic Fields

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There is an apparent involvement of thermal damage in the case of high-intensity irradiation, but conventional heating does not appear to cause equivalent levels or types of chromosomal damage as compared with those resulting from RFEM fields. 2 Mutagenic Effects Mutagenic effects of RFEM radiation have been investigated in a limited number of biological systems. No effects on the incidence of sex-linked lethal mutations were detected by Mittler (1976), who 44 / 4. CHROMOSOMAL AND MUTAGENIC EFFECTS exposed Drosophila melanogaster either to 29-MHz fields at 600 V/m or to 146-MHz fields at 63 V/m for 12 hours.

Cells examined one week post exposure showed reduced stickiness compared with immediate post-exposure samples, but structural aberrations, including breaks and rearrangements, occurred at significantly higher incidence in exposed cells. The nature of the chromosomal aberrations indicated that multiple mechanisms may be involved in the induction of chromosomal breakage by such exposure. 25 to 600 kV/m for periods of 5 min to 8 h induced stickiness in chromosomes, which led to clumping, pyknosis, and the formation of bridges during anaphase and telophase (Mickey, 1963).

I t must be noted, however, that effects of chronic exposure have not been adequately investigated. There is an apparent involvement of thermal damage in the case of high-intensity irradiation, but conventional heating does not appear to cause equivalent levels or types of chromosomal damage as compared with those resulting from RFEM fields. 2 Mutagenic Effects Mutagenic effects of RFEM radiation have been investigated in a limited number of biological systems. No effects on the incidence of sex-linked lethal mutations were detected by Mittler (1976), who 44 / 4.

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