By Darius M. Dziuda

ISBN-10: 0470163739

ISBN-13: 9780470163733

ISBN-10: 0470593407

ISBN-13: 9780470593400

Info Mining for Genomics and Proteomics makes use of pragmatic examples and an entire case learn to illustrate step by step how biomedical reports can be utilized to maximise the opportunity of extracting new and precious biomedical wisdom from info. it truly is a good source for college students and execs concerned with gene or protein expression facts in various settings.

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Additional resources for Data Mining for Genomics and Proteomics: Analysis of Gene and Protein Expression Data (Wiley Series on Methods and Applications in Data Mining)

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2007; Gingeras 2007; Zheng et al. 2007). † 16 Some of these nonprotein-coding RNA transcripts are well known functional RNA molecules, for example ribosomal RNAs (rRNA) or transfer RNAs (tRNA). Others include recently discovered microRNAs (miRNA) and small interfering RNAs (siRNA); both of them can regulate expression of specific genes (Gingeras 2007). 3: A human protein-coding gene: the structure, transcription, splicing, and translation. The top row shows a schematic structure of the gene. The transcribed region consists of exons that are interrupted by introns (on average, introns are about 20 times longer than exons).

Others include recently discovered microRNAs (miRNA) and small interfering RNAs (siRNA); both of them can regulate expression of specific genes (Gingeras 2007). 3: A human protein-coding gene: the structure, transcription, splicing, and translation. The top row shows a schematic structure of the gene. The transcribed region consists of exons that are interrupted by introns (on average, introns are about 20 times longer than exons). The promoter associated with the gene is a regulatory sequence that facilitates initiation of gene transcription and controls gene expression.

Alternative splicing—generally, combining different subsets of gene exons to form (code for) different mRNA transcripts (see Fig. 4). Alternative splicing invalidated the “one gene—one protein” paradigm. † Nonprotein-coding genes—genes that “encode functional RNA molecules16 that are not translated into proteins” (HUGO Gene Nomenclature Committee 2008). † Overlapping protein-coding genes—genes sharing the same DNA sequence. New exons have been discovered far away from the previously known gene locations, some of them within the sequence of another gene (Pennisi 2007).

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Data Mining for Genomics and Proteomics: Analysis of Gene and Protein Expression Data (Wiley Series on Methods and Applications in Data Mining) by Darius M. Dziuda


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